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Ashwini and her partner Tanisha Crasto suffered their third straight loss in the women's doubles competition of the Paris Games.
However, young Indian shuttler Meiraba Luwang Maisnam's splendid run came to an end.
Sathish, who won men's singles title at India International and had a runner-up finish at Maldives International this season, prevailed over Ayush in an exciting final.
The world No. 32 Indian pair went down fighting to third seeds Rin Iwanaga and Kie Nakanishi of Japan in a 77-minute clash.
Results 1-4