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Shelton showed he could be a threat over the next two weeks as he broke Thiem again to close out the second set.
Nadal marked his singles comeback after hip surgery with a victory over Austrian former world No. 3 Dominic Thiem in the Brisbane International first round..
Austrian Thiem, who has failed to win a match at any of the tournaments he has played since his wrist injury comeback in March, made 42 unforced errors as his once dominant claycourt game deserted him.
The 28-year-old Austrian has not played since suffering the injury at the Mallorca Open in June.
The 27-year-old said that a right wrist injury will keep him out of action for several weeks.
Two-time former champion Petra Kvitova slumped out of Wimbledon in the first round, beaten by inspired world No. 50 Aliaksandra Sasnovich.
Rafael Nadal failed to win a single game in the opening set against Dominic Thiem but fought back to beat the Austrian 0-6, 6-4, 7-5, 6-7(4), 7-6(5).
Khachanov will now play his first Masters 1000 final on Sunday against the winner of the blockbuster second semi between Novak Djokovic and Roger Federer.
The 32-year-old Djokovic, seeded second in the tournament, got the decisive break in the third game of the final set against the Austrian to win his eighth Australian Open title.
World No. 3 Dominic Thiem of Austria and Bulgarian Grigor Dimitrov, who is ranked 19, have confirmed their participation in the eight-man event.
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