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Toy maker Mattel unveiled the dolls on Wednesday, each with their bespoke accessories.
In a recent video shared on her YouTube channel, the seven-time Grand Slam singles champion expressed her aspirations to participate in the WTA 1000 events in Indian Wells and Miami, considering them 'big goals'.
Belgian qualifier Greet Minnen smacked 24 winners and saved all six break points she faced to dispatch the veteran American.
Venus, 43, has won the third major of the year five times and returned to action this month after a five-month injury layoff.
The Los Angeles TGL franchise is part of the Ohanian family's growing sport portfolio.
Her withdrawal comes a day after American seven-time Grand Slam champion Venus Williams was ruled out of the Australian Open due to injury.
The WTA Tour will not be the same without Serena. She was a symbol of fighting spirit, pride and strength on the court and her legacy will be tough to match.
Winners of 14 Grand Slam doubles titles, including two US Opens, the Williams sisters were playing together for the first time in more than four years.
Venus lost to Alison Van Uytvanck and Emma Raducanu was defeated by Aliz Cornet. Osaka lost to Danielle Collins.
The field still boasts world No. 1 and reigning Wimbledon champion Ash Barty, four-time Grand Slam winner Naomi Osaka and reigning French Open champion Barbora Krejcikova.