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The book, written in German, tells the story of a young woman's "destructive affair" with an older man in 1980s East Berlin. The book has been translated to English by Michael Hofmann.
The novel, Lynch's fifth, seeks to show the unrest in Western democracies and their indifference towards disasters such as the implosion of Syria.
The book beat five other finalists to the prize, which recognizes fiction from around the world that has been translated into English.
The winner of International Booker Prize 2022 will deliver the M R Narayana Kurup memorial talk.
The judges' unanimous choice, "The Seven Moons of Maali Almeida" is the darkly humorous story about a murdered war photographer investigating his death and trying to ensure his life's legacy.
The award-winning author said her mother, the renowned educationalist, who died Thursday, was a miracle.
'The Satanic Verses' writer was stabbed in the neck and torso on Friday at an event in New York by a 24-year-old New Jersey resident Hadi Matar.
Tomb of Sand houses many good people. The source of the goodness of humanity in the world of the novel comes from the warm, hopeful, radiant personality of the author.
In a congratulatory message, Prof Mansoor said it is rare that a novel from a non-European language got the highest honour and it is the acknowledgement of Indian cerebral power.
Tomb of Sand, originally 'Ret Samadhi', is set in northern India and follows an 80-year-old woman in a tale the Booker judges dubbed a joyous cacophony and an 'irresistible nove'".
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