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Saina lost to world No. 8 South Korea's Sung Ji-hyun 22-10, 8-21, 14-21 in the opening round.
PV Sindhu rallied to down Busanan Ongbamrungphan of Thailand 21-23, 21-13, 21-18.
India's top shuttler Sindhu beat Xuerui 21-18, 21-12 in just 34 minutes to seal a place in the pre-quarterfinals.
World No. 26 Satwik and Ashwini showed their grit as they recovered from a mid-game slump to outwit sixth seeds Praveen Jordan and Melati Daeva Oktavianti 22-20, 17-21, 21-17.
Almost a month after dispatching Ginting en route to his World Championships bronze at Basel, world No. 15 Praneeth went down to the 21-16, 6-21, 16-21 in 55 minutes to end his campaign.
Doubles specialist Satwiksairaj Rankireddy also had a dismal day as he suffered twin defeats, losing both the men's doubles and mixed doubles pre-quarterfinals.
World No.6 Sindhu, who made early exits in China, Korea and Denmark, lost 13-21 21-18 19-21 to world No.42 Pai in a 74-minute women's singles match.
Both B Sai Praneeth and Parupalli Kashyap bowed out of the competition after losing their respective second-round matches.
Saina Nehwal's poor run of form continued as the Olympic bronze-medallist lost to local favourite Cai Yan Yan in straight games.
The world No. 9 Indian pair lost 16-21, 20-22 to the top seeds Marcus and Kevin of Indonesia.
Results 1-10 of 12