Washington: E coli food poisoning linked to McDonald's Quarter Pounder hamburgers has sickened at least 49 people in 10 US states. One person died, and 10 were hospitalised due to food poisoning, federal health officials said Tuesday.

The death was reported in an older person in Colorado, and one child has been hospitalized with severe kidney complications, the US Centers for Disease Control and Prevention reported.

Infections were reported between September 27 and October 11, in Colorado, Iowa, Kansas, Missouri, Montana, Nebraska, Oregon, Utah, Wyoming and Wisconsin. Colorado has the most cases, 27, followed by Nebraska with nine.

Everyone interviewed in connection with the outbreak had reported eating at McDonald's before falling ill, and most mentioned eating Quarter Pounder hamburgers, the CDC said. The US Agriculture Department, the Food and Drug Administration and state health officials are also investigating.

The specific ingredient tied to the outbreak has not been identified, but investigators are focused on onions and beef. McDonald's reported to the CDC that it had removed slivered onions and beef patties used for Quarter Pounders from stores in the affected states. The burgers may be temporarily unavailable in those states.

E. coli bacteria are harboured in guts of animals and found in the environment. Infections can cause severe illness, including fever, stomach cramps and bloody diarrhea.

People who develop symptoms of E coli poisoning should seek health care immediately and tell the provider what they ate. The Associated Press has reached out to McDonald's for comment.

The news comes in an already tough year for the Chicago-based chain. In the second quarter, its global same-store sales fell for the first time in nearly four years as inflation-weary customers skipped eating out or chose cheaper options. The company responded with a $5 meal deal, which was introduced at US restaurants in late June and recently extended through December. The deal doesn't include the Quarter Pounder.

McDonald's shares dropped 9% in after-hours trading Tuesday after the CDC's announcement.

The type of bacteria implicated in this outbreak, E. coli O157:H7, causes about 74,000 infections in the US each year, leading to more than 2,000 hospitalizations and 61 deaths. Infections are especially dangerous for children younger than 5 and can cause acute kidney failure.